Enhanced corrosion protection of Mg-based alloys for implants

A recently published study describes cellulose nanocrystal reinforced silk fibroin coating for an enhanced corrosion protection and biocompatibility of Mg-based alloys for orthopedic implant applications.

Medical staff in the operating theatre.
Biofilms on surfaces causes persistent infections and is an issue of considerable concern to healthcare providers. Image source: sasint - Pixabay (symbol image). 

A novel coating material based on silk fibroin (SF) and cellulose nanocrystals (CNCs) was developed on biodegradable AZ31 Mg alloy and assessed for corrosion resistance and biocompatibility. Before the application of the coating, the AZ31 substrate was modified with a layer of polydopamine to enhance the adhesion of the protective coating to the metal surface as confirmed by the adhesion tape test. SEM images revealed the formation of a defect-free and uniform SF-CNC coating with a thickness of 11.2 ± 2.5 μm on AZ31 alloy.

Enhanced corrosion resistance

The results of the electrochemical corrosion and in vitro immersion tests clearly demonstrated an enhanced corrosion resistance of the SF coating after the incorporation of CNCs. Compared to the unmodified Mg alloy, the SF-CNC coated AZ31 exhibited a remarkably improved cytocompatibility. As the researchers pont out, the findings of their work highlight the great potential of SF and CNC as bio-based nature-derived anticorrosive nanofillers for fabrication of protective and biocompatible coatings on Mg-based biodegradable orthopedic implants.

The study has been published in Progress in Organic Coatings, Volume 161, December 2021.

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