Cyclised/knotted poly-divinyl-benzene (Pdvb) antibacterial coatings

Microbial active ingredients are limited due to their risk assessment. It is still mandatory to have antibacterial coatings especially in the medical industry. This new approach offers a solution to this dilemma.

The spread of bacteria should be prevented everywhere, especially in the medical environment. Coatings can help in the routine.
The spread of bacteria should be prevented everywhere, especially in the medical environment. Coatings can help in the routine. Source: New Africa - stock.adobe.com

In the medical industry, minimising biofouling is of utmost importance as it helps to reduce bacterial adhesion and prevent cross-infection. In this study, cyclized/knotted poly-divinyl-benzene (PDVB), a polymer with distinctive structural features, is proposed for the first time to be utilised in the preparation of antibacterial coatings.

Firstly, cyclized/knotted PDVB is synthesised via deactivation-enhanced atom transfer radical polymerisation (DE-ATRP). Subsequently, it is processed into coatings by employing the “grafting to” method. The obtained PDVB coatings display remarkable antibacterial activity on both glass and titanium alloy substrates owing to their unique cyclised/knotted structure, effectively inhibiting the proliferation of common pathogenic bacteria. Additionally, the coatings also exhibit excellent hydrophobicity, strong adhesion, and superior thermal stability. These research findings suggest that cyclised/knotted PDVB coatings possess outstanding physicochemical properties and demonstrate powerful antibacterial performance. It is anticipated to open up new avenues for antibacterial materials.

Source: SSRN

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