Rosemary coating for surgical steel

Researchers have discussed rosemary loaded xanthan coatings on surgical grade stainless steel for potential orthopedic applications.

Natural herbs like henna, rosemary, thyme, moringa are preferred to introduce antibacterial effects. Image source: samsevents - Pixabay (symbol image).

The demand for orthopedic implants coated with biocompatible and bactericidal materials is escalating because of the rising bacterial resistance against synthetic antibiotics. Consequently, a non-toxic polysaccharide infused with the natural herb, i.e., Xanthan (Xn) and Rosemary (Rm) were coated on surgical grade stainless steel (316 L SS). Electrophoretic deposition (parameters were optimised through a trial-and-error approach) was employed to coat a thin film of Xn with uniformly dispersed Rm in the matrix. The uniform distribution of Rm in the said coating was confirmed by field emission scanning electron microscopy. Fourier transform infrared spectroscopy (FTIR) also confirmed the loading of Rm.

Biocompatible and bactericidal coating

The self-crosslinking capability of Xn at acidic pH (confirmed by FTIR) provided sufficient adhesive strength with substrate confirmed via scratch test and bend test. Thereafter, the suitable surface topography for enhanced integration was studied in terms of surface roughness and wettability. The bacterial resistance and cellular interactions of both Xn and Rm were revealed by WST-8 and disc diffusion assay, respectively. Hence a biocompatible and bactericidal coating on 316L SS with suitable surface topography was developed with a novel combination of Xn and Rm.

The study has been publihed in Progress in Organic Coatings, Volume 186, January 2024.

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